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1.
Chinese Journal of Surgery ; (12): 256-259, 2023.
Article in Chinese | WPRIM | ID: wpr-970188

ABSTRACT

Endovascular treatment of Stanford type B aortic dissection (type B dissection) has been widely used. There will be complications such as aortic dilatation, which will lead to poor prognosis of some patients. With more in-depth researches, it was found that there was a possible correlation between the prognosis of type B dissection and tears, such as the increasing of aortic diameter would be faster with longer tears, and the location of the tear will affect the thrombosis of the false lumen. Studies on hemodynamics have also found that different characteristics of tears of aortic dissection can cause changes in the pressure, blood flow rate and blood capacity in the true and false lumens recently. The hemodynamic changes can be used to predict the prognosis of type B dissection. The main characteristics of tears included the size, position, number of tears, residual tears and stent graft induced new entry. Describing the effect of tear characteristics on the development of type B dissection, can provide the basis for the clinical treatment and further research of type B dissection.


Subject(s)
Humans , Aortic Dissection/surgery , Hemodynamics , Prognosis , Blood Vessel Prosthesis Implantation/adverse effects , Thrombosis/etiology , Endovascular Procedures/adverse effects , Aortic Aneurysm, Thoracic/surgery , Stents/adverse effects , Treatment Outcome
2.
China Journal of Chinese Materia Medica ; (24): 2917-2921, 2012.
Article in Chinese | WPRIM | ID: wpr-338062

ABSTRACT

<p><b>OBJECTIVE</b>To compare the difference of chemical constituents of Cinnamomi Ramulus and Cinnamomi Cortex,and study the characteristics of their chemical constituents, in order to provide basis for clinical application and quality control.</p><p><b>METHOD</b>HPLC fingerprint method was used to analyze chemical constituents of Cinnamomi Ramulus and Cinnamomi Cortex compare the difference between.</p><p><b>RESULT</b>Cinnamomi Ramulus and Cinnamomi Cortex had similar HPLC fingerprint profiles, but with difference in peak areas of their chemical constituents. Specifically, the average peak areas of cinnamyl alcohol, cinnamic acid and 2-methoxy cinnamic acid were higher than that of Cinnamomi Cortex, whereas the average peak areas of 2-hydroxyl cinnamaldehyde, coumarin, cinnamaldehyde and 2-methoxy cinnamaldehyde in Cinnamomi Cortex were higher than that of Cinnamomi Ramulus.</p><p><b>CONCLUSION</b>This method can be used for evaluating quality of Cinnamomi Ramulus and Cinnamomi Cortex. The ratio between the peak areas of cinnamaldehyd and cinnamic acid can be used to discriminate most Cinnamomi Ramulus samples (<23) and Cinnamomi Cortex samples (>23). Cinnamomi Ramulus and Cinnamomi Cortex have the similar types of chemical constituents but with difference in content. This study provides reference for the pharmacodynamic difference of Cinnamomi Ramulus and Cinnamomi Cortex.</p>


Subject(s)
Chromatography, High Pressure Liquid , Cinnamomum , Chemistry , Cluster Analysis , Drugs, Chinese Herbal , Chemistry , Reference Standards
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